So I'm once again perusing the thread for assistance, so hopefully my issue has already been conquered.
Here's my build, which is running in horizontal orientation:
i7-8700K (throttled to run like an i5-8400 for TDP purposes)
1080 Ti FE
16GB RAM (Corsair Vengeance LPX 3600)
Asrock Fatal1ty Z370 Gaming ITX
2x WD 2TB notebook spinners
1TB 860 EVO M.2
Corsair 600W Gold SFX
Noctua NH-L9i e/w NF-B9 Redux Fan
I get that I'm well above TDP on the video card, but at least it's a blower. I have ordered taller feet so that it can breathe better, but that's in progress.
The issue is that I'm cooking "Drive 2". I haven't traced the cables to see which wound up being spinner #2, but it's hitting 80C during gaming. Everything else is fine, and I could push the CPU harder.. though the GPU could use some undervolt tweaks. I started looping the new Forza Horizon 4 Demo to examine temps and such when I discovered this. Thoughts?
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You could try mounting the hdd below the GPU near the blower inlet - it actually works magic for the drive temp, at least with GTX 970 we've tested. 1080 TI is really power hungry and hot so it will give off that heat to drives especially in horizontal position. It should be a lot better on vertical stand for such config.