My dudes, i have discovered how to keep Pixel Shift turned off. Go to the Settings -> General -> Additional Settings and turn off "Quick Start+". Now the Pixel Shift button works "as intended" and keeps the setting off when power cycling the TV. Thank goodness i dont have to do that every morning anymore...
Must have something to do with the way LG makes the TV "sleep" when using the Quick Start+ option.
The caveat of this is that it takes longer for the display to start, let you change inputs etc. I kept Quick Start+ on because it works better for my usage patterns where I turn off the TV during larger breaks. At 4K 60 Hz screen shift on or off doesn't have any bearing on image quality as far as I can see.
I just hope LG simply fixes the problem because it's clearly a bug.