Hell no! I'm getting a more closed look at this case since a few days and was curious about those holes. For structure rigidity and aesthetic purpose there need to be this kind of mesh but of course it's blocking some air flow compared to a plain hole.- would also be nice if the perforations on all panels were smaller so they had a finer aesthetic quality.
My guess is a fan stickied to the perforations panel will do better than same fan at 10mm distance but I'm no expert.
Was wondering how to improve air flow and keep it aesthetic. Was thinking of this mod doable with a Dremel, I only did a small section:
And even better airflow but a tad less rigidity, should do just fine too (nobody should touch there anyway):
This is only required when having a fan pushing air through mesh which should improve air flow quite a bit.