There's really no need for saving that space for a home server though, not to mention that ITX boards have less sata ports and expansion slots. If anything, it's still for the purpose of decor and looks.
most ITX boards have 6 sata and one PCI-E x16 is all you need for an eight port SAS2 HBA, which you can also use an expander with.
If you had a standard size 9x5.25" bay mid tower case with 3x4in3 or 5in3 bays plus fill the bottom of the case with internal drive mount you would have much higher disk density in the same size case or be able to cram 12 drives in a much smaller case. You don't NEED a home server to be tiny, but you also don't NEED to have a SFF desktop either.
Silverstone had an 8bay steel / alu front ITX case at Computex this year, DS380. Looked like a pretty cheap product, plastic hotswaps and unpainted interior.
What a fat looking POS
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