Wow, one of the developers has just announced that a new version of Core 14 has been released and it fixes all the problems associated with mismatched shader counts and mismatched card generations.
ihaque said:A new Nvidia Core_14 (v1.26) has been posted. This build includes a fix that addresses problems people were having on multi-GPU systems with mismatched cards. Note that this does not include any checkpointing changes (as included in Core_11 v1.31). This should solve the problems people have had running FAH core 14 with mismatched cards - both mismatched shader counts and mismatched card generations should work now.
To update an existing folding system, you can stop the client, delete FahCore_14.exe and restart the client. The new version will be downloaded the next time a core 14 WU needs to be processed.