Go into Setpoint and check to make sure that the side to side buttons are bound to do horizontal scroll. Also, Setpoint may need to be running in order to use the advanced buttons on the mouse, but it should be automatically launching at startup. And obviously, you can only horizontal scroll on a page that has a horizontal scrollbar (i.e, one that is wider than the size of you screen).
![[H]ard|Forum](/styles/hardforum/xenforo/logo_dark.png){kind=logo}