Well, the numbers are showing it's really not. If a 48-shader 9600 GSO can handle the job fairly well and a GT 640 can handle it as well as a GTX 580 SC, the PhysX in BL2 clearly isn't THAT demanding.
I would agree but the 20% FPS performance boost seems to state otherwise (GTX 680 alone versus GTX 680 with GT 640 OR GTX 580 SC). I guess it just seems any decent GPU will help performance when dedicated to PhysX.