No flame intended --why would you wish to run Norton, when Avast! is so much better, free of charge, and the current version runs quite well on Vista?
I'm running the latest version of Avast! Antivirus on Vista RC2, and it works quite well. Far better than the eTrust and PC-Cillin AV suites that I've also tried. Like Norton, the other two take up more disk space and RAM, and have additional features that most users don't need (i.e., firewall that overrides the fairly decent one native to Vista).
My prob is Vista says no Norton products that are 2005 or older, but Norton password manager is 2004. So even if you have the newer version of Systemworks, password manager is still 04, so im hosed. I installed it but it wouldnt run properly. Havent seen any work arounds from symantec yet.
First, it's Vista. Good luck getting a virus until it actually becomes mainstream and viruses are actually written for it. Second, I would think that an Anti Virus system designed to work with XP would have limited usefulness in a different OS.