MSI is a product name that I respect and count on. I have had many MSI products including a number of video cards and motherboards. MSI is doing it right!
I have to admit, I like the general idea of the Twin Frozr HSF, but after trying a GTX 465 Twin Frozr Golden Edition I discovered its a tad noisy in my small Lian Li "upside down" case. The GPU is situated close to the 140mm blow hole fan and the GPU's fan is noticeable when it ramps up above 40%. I returned it and got a PNY GTX 460 1GB with the reference cooler and its nearly silent (even being near that fan opening at the top of my PC).
I've been impressed by their products so far, but some of the warranty stuff (like on laptops is LAME - the power cable that comes with your laptop only has a 90-day warranty... maybe that's just the norm now though)
I kinda half expect that if your card dies from a fan failure that they'd tell you it's not covered since the fan only had a 90 day warranty
Here's crossing my fingers that my case was an exception than the standard
I've been a fan of the TwinFrozr series for a while, and this card looks pretty good. I have an older TwinFrozr GTX 260 and I've got nothing but good things to say about it.