how do i know if game uses crossfire?

[EquaLiZr]

Well im trying to play serious sam the 2nd encounter and im running the latest 11.11 drivers and downloaded MSI afterburner to monitor crossfire. SS is not working with crossfire So i got Radeon pro and tried different profiles and was able to get crossfire but every once in a while the game would stop for a few seconds then start up again.