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The z-2300's would be a good bet if your looking for something less expensive with a heavy sub in the 2.1 PC speakers department. I've had a couple sets of them and they sound pretty good. I just upgraded to the z-5500's though and HOLY CRAP!!
If you've got the right connectors you can hook a car subwoofer up to a home sound system, but be forewarned, a car subwoofer won't sound as great as it does in a car as it will in your room, the sound environment is MUCH different.