Oh hell yes, I need to turn down my environment, those fucking shadows make it near impossible to find people half the time, the only reason you need a super pretty image is cause you're staring at it while you're dead!
Rig in sig, running at 1920x1200 with ultra everything and high FSAA + 2X MSAA (no motion blur because it looks like shit). Averaging about 75 FPS, rarely dips below 60. Smooth as butter.
I tuned this down from 4X MSAA because I was dropping below 60 FPS and seeing some microstutter, however this may be improved since I installed the unofficial CAP4. I'll have to try it.