Corrupt HDD question

[BigDonkey2]

I have a 120GB Maxtor that is just used as storage. I have about 75GB of used space on it. I just put a new mobo in (Epox 8KRAI-X) and now when I click on it it says that its corrupt and cannot be read. Is there anyway that I can recover these files? With my old mobo (Epox 8KHA+) it would sometimes work and sometimes not, but for the most part it would work and now it doesnt. Whats the deal? Am I screwed? Thanks in advance.

-Big D