That's probably going to be board dependent. A lot of the Z170 boards still have their external clock generators from when you could overclock normal Skylake chips using the base clock. Even though that ability was taken away in a microcode update to the CPU by Intel, there was no sense in redesigning the boards just because of it. So that means you may find you're M2 slot is on a different clock plane than your Bclk and have no problems depending on your board. On the MSI board I was using previously, the M2 slots took their capacity from the SATA.SATA express plane. So it may have not had any problem with a Bclk rise but I haven't bothered to buy a M2 yet to find out
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