![[H]ard|Forum](/styles/hardforum/xenforo/logo_dark.png){kind=logo}
Gilthanis
[H]ard|DCer of the Year - 2014
- Joined
- Jan 29, 2006
- Messages
- 9,046
Data from Help Stop Muscular Dystrophy Project Used to Examine Protein Function
Dr. Alessandra Carbone, who led the Help Cure Muscular Dystrophy Project, recently published a paper that used data from the project to examine protein function and protein-protein interaction.
Proteins are the all-important molecules involved in biological processes and machinery in cells. Their interactions with each other and other molecules control and implement their functions. Thus it is important to understand whether they interact, and specifically how they interact. The complex surfaces of proteins present patterns of attractive and repulsive electric charges which match to a varying degree the opposite pattern of charges on other molecule surfaces. Understanding which of possibly many portions of the surface of a protein are most responsible for reactions with other molecules and proteins are key to understanding their functions.
This open-access paper describes the researchers' efforts and helpful techniques in identifying and classifying the surface interaction sites of proteins using results calculated in Phase One of the Help Cure Muscular Dystrophy project, which ran on World Community Grid from December 2006 to June 2007.
Dr. Alessandra Carbone, who led the Help Cure Muscular Dystrophy Project, recently published a paper that used data from the project to examine protein function and protein-protein interaction.
Proteins are the all-important molecules involved in biological processes and machinery in cells. Their interactions with each other and other molecules control and implement their functions. Thus it is important to understand whether they interact, and specifically how they interact. The complex surfaces of proteins present patterns of attractive and repulsive electric charges which match to a varying degree the opposite pattern of charges on other molecule surfaces. Understanding which of possibly many portions of the surface of a protein are most responsible for reactions with other molecules and proteins are key to understanding their functions.
This open-access paper describes the researchers' efforts and helpful techniques in identifying and classifying the surface interaction sites of proteins using results calculated in Phase One of the Help Cure Muscular Dystrophy project, which ran on World Community Grid from December 2006 to June 2007.