no, unless your monitor is capable of displaying the image at 1:1 and then you'll have black borders to fill the unused pixels. If your monitor supports a resolution with exactly 1/4 the pixels, it can look pretty clear as each pixel becomes 4. So a 1600x1200 monitor (with 1,920,000) will look pretty clear at 800x600 (with 480,000 pixels). But if you want 1680x1050 to look as good as native on a 1920x1200 display, you're out of luck. Such is the trade-off with an ultra-sharp (at native) LCD.