Question about enabling "Hardware Memory Hole"

[commissioneranthony]

Does this have any negative drawbacks to my system? I am using an ASUS A8N CSM motherboard and it recognizes 3gb ram+ when memory hole enabled but only recognizes ~2.8gb when disabled. Is it detrimental to the system's stability to enable this option? I can't OC on the board, cause the bios is horrid, so otherwise the stability could only be affected by this memory hole enabeling. Any help would be greatly appreciated. Thanks.