Fractal Design S Nano

Does anyone think that a 2.5 slot card will fit in this case, using a Silverstone SFX PSU with adapter plate?
I currently have a Gigabyte Xtreme GTX1080 that I am trying to fit in the smallest case possible.
 
Would not do a water-cooled build in this chassis with a 1060, no one makes water blocks for the 1060s that are short enough to fit with a radiator & full thickness fans up front… No water blocks for the 'shorty' ITX sized 1060s, and no reference length 'full-size' 1060s out the; excepting the nVidia reference model, which EK does NOT make a full cover water block for…

Specificlally why I mentioned the Gigabyte GTX 1070 ITX GPU as the one I would love to see a full-cover block for…

Which is why I would like to see another version of this chassis for air cooling and the accompanying reduction in size. An ~18L-ish Define S style as opposed to the oversized 26L model at the bottom of the Fractal Define S line.
 
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