This is taken directly from Diskeeper's website. I'd be inclined to say that having such a large hold across the Fortune 500 companies indicates something is going right. Generally these technologies trickle down to the home-user level.
COD:MW gave me some fun multiplayer times.
COD:MW2 gave me a fun (albeit short) single player experience.
COD:BO had a less engaging single player along with a shoddy multiplayer experience.
Yeah Treyarch... I, as well as many others, feel the latest iteration pushed the envelope too far...
You could also look in to trying out HyperFast by Diskeeper Corporation.
They've got a white paper on it below:
http://downloads.diskeeper.com/pdf/Optimizing-Solid-State-Storage-with-HyperFast-Technology.pdf
Their defrag program is more designed towards corporate/enterprise...