I have my SX 350 3.2TB working just fine in proxmox. Putting your storage volume of choice on top of it is manual though since the GUI doesn't enumerate /dev/fioX devices.
3 copies of your data on 3 different media.
1) Online active 50TB array
2) Replica array ideally in another building/datacenter/region
3) Offline copy on external bricks/Iron Mountain/cloud bucket/etc.