I'm talking about auto-aim ultimate abilities, which really aren't about the game being on PC or console and more about having a powerful ability. I'd prefer that those abilities be skill based (i.e. a quad damage power-up still requires you to aim and hit other players).
Blizzard already removed auto-aim options from the rest of the game (i.e. the stuff you normally see implemented for console controllers) so I'm not worried about that.
Learn the sound effects for the ultimate abilities. For example, when I hear the "It's High Noon" track play, I immediately hide behind the closest wall. Works well unless you're caught in the open when they trigger the ability.