cybereality
[H]F Junkie
- Joined
- Mar 22, 2008
- Messages
- 8,789
End of the year can't come soon enough.
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IF all 45 have neutralizing antibodies, it's significant, because, as I recall, the phase 1 trial only had 45 people. I'm a bit confused about phase 2, since I saw an article that they were just starting Phase 2 earlier this month, but they're also starting phase 3 on 7/27.WOOOOOO 45 people! WOOOOOOOOOO. However you feel about the USA (as a whole and at the top) and its handling of this thing, the media is as always part of the problem. If you don't want people to break out and spread this quit lauding useless results in headlines. I have felt Fauci has been good for you, but when its his lab that is coming out with this of course he's positive about the results. But 45 people come on. As pointed out before, HIV vaccines have had successful Phase 1 trials.
Just shut up about it and try to keep your public following reasonable guidelines.
A local government can use eminent domain to take (with proper compensation which isn't always fair) someone's house if it means allowing a PRIVATE entity to develop the area in such a way that makes the locality an overall improvement. Yet here we have property... some patent... and it could possibly help the locality by allowing some other private entity to use it... yeah fuck this country and it's patent system.
And yet there is an almost free treatment that works almost 100 percent of the time that was dragged through the mud because well... You knowRemdesivir for coronavirus: Gilead to charge thousands for treatment in U.S.
https://www.nbcnews.com/health/heal...ilead-charge-thousands-treatment-u-s-n1232385
"First Phase 3 clinical trial of a coronavirus vaccine in the United States begins" -- https://www.cnn.com/2020/07/27/health/coronavirus-vaccine-trial-begins-moderna-phase-3/index.html
If you mean Hydroxychloroquine, only one study shows it works. The rest conclude it does more harm than good. That said, there is a cheap steroid, that studies show works about 1/3 of the time. https://www.sciencemag.org/news/202...rst-drug-shown-reduce-death-covid-19-patients.And yet there is an almost free treatment that works almost 100 percent of the time that was dragged through the mud because well... You know
Studies so real they have to be retracted cause the biggest one was more bullshit than science?If you mean Hydroxychloroquine, only one study shows it works. The rest conclude it does more harm than good. That said, there is a cheap steroid, that studies show works about 1/3 of the time. https://www.sciencemag.org/news/202...rst-drug-shown-reduce-death-covid-19-patients.
"First Phase 3 clinical trial of a coronavirus vaccine in the United States begins" -- https://www.cnn.com/2020/07/27/health/coronavirus-vaccine-trial-begins-moderna-phase-3/index.html
Studies so real they have to be retracted cause the biggest one was more bullshit than science?
Chinavirus is like climate-science
fucking religion.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1232869/
2005 study.
Before it could be politicized.
Hydroxychloroquine is an entry inhibitor that could work early on but needs to be administered along with other kinds of drugs which have different mechanisms such as Doxycycline or Azithromycin
Hydroxychloroquine was banned by governors because it was politicized not because it didn't work.This is a strange disease where 1 drug alone doesn't work by itself. We need a cocktail of drugs & the content of the cocktail also changes by the timing of the intervention.
Hydroxychloroquine is an entry inhibitor that could work early on but needs to be administered along with other kinds of drugs which have different mechanisms such as Doxycycline or Azithromycin
Likewise in Iran a study found success with combination of Hydroxychloroquine with Bromhexine
In US independent studies have been very difficult to initiate as opposed to pharma backed studies. For ex. Dipyridamole a very promising drug got very few enrollments because it is not backed by any pharma.
Whereas other countries have managed successful trials for cheap drugs such as Dexamethasone in Uk & Colchicine in Greece
As of now the most promising/affordable treatment in horizon seems to be nebulized/inhaled interferons. Already a british pharma has done a study on it. It is only a matter of time before US pharma catches on to this
Theoretically speaking, In Silico models, highlight Niclosamide as a drug with huge promise. But the bio-availability of Niclosamide is very poor. That is a challenge that has to be overcome.
All of the above are cheap drugs too like dexamethasone/methylprednisolone
Fingers crossed that we will soon (by the end of the year??) have affordable alternatives to Remdesivir & Tocilizumab
Hydroxychloroquine was unfortunately politicized which is awful. According to the media taking the drug will kill you. As opposed to last year, when it was readily used across the world.
Just when I thought I had read the dumbest thing on the internet ... this gem pops up. It is amazing how certain countries turn public health issues into political ones. Sad really. Good luck with all that .Studies so real they have to be retracted cause the biggest one was more bullshit than science?
Chinavirus is like climate-science
fucking religion.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1232869/
2005 study.
Before it could be politicized.
You think it's dumb when a "study" that was used as an excuse to stop all trial use of a life saving drug that resulted in people dying was all made up and later retracted because it was made up out of thin air?Just when I thought I had read the dumbest thing on the internet ... this gem pops up. It is amazing how certain countries turn public health issues into political ones. Sad really. Good luck with all that .
You do realize that's a different strain right? And that drugs effect strains differently. So while that study is before things got politicized, it might ultimately be irrelevant to the current strain.Studies so real they have to be retracted cause the biggest one was more bullshit than science?
Chinavirus is like climate-science
fucking religion.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1232869/
2005 study.
Before it could be politicized.
You do realize that's a different strain right? And that drugs effect strains differently. So while that study is before things got politicized, it might ultimately be irrelevant to the current strain.
Humans share 80% of DNA with cows. How about that?80 percent the same
You never came back to the soapbox threadHumans share 80% of DNA with cows. How about that?
Why would I ever want to touch that pile of crap again?You never came back to the soapbox thread
LolWhy would I ever want to touch that pile of crap again?
Doesn't matter if they're 99% identical. For example, in TB the majority of drug resistances between strains come from single nucleotide polymorphisms. And those are for drugs where we actually know the mechanism of action, which in the case of the paper you provided remains unclear for SARS-COV1 and chloroquine.80 percent the same
It actually does because it infects humans the same way.Doesn't matter if they're 99% identical. For example, in TB the majority of drug resistances between strains come from single nucleotide polymorphisms. And those are for drugs where we actually know the mechanism of action, which in the case of the paper you provided remains unclear for SARS-COV1 and chloroquine.
n one study, Business Insider reports that a team of scientists from the Wuhan Institute of Virology observed samples of the virus from seven patients who appeared to have “severe pneumonia.” Six of these patients worked at the Huanan seafood market in Wuhan where experts believe the outbreak started.
After analyses, approximately 70 percent of the samples were “nearly identical” to each other. Their genetic sequence was even more similar to SARS, boasting a 79.5 percent similarity.
A second study conducted by researchers from Fudan University in Shanghai and the Chinese Center for Disease Control and Prevention examined a single person: a 41-year-old man who worked at the same seafood market.
The patient, who exhibited similar respiratory symptoms and a fever, was determined to be infected with a virus that was 89 percent similar to a group of “SARS-like coronaviruses” known as betacoronaviruses, previously identified in bats.
These similarities led researchers to find that the Wuhan coronavirus and SARS bind to human cells the same way, latching on to the same cellular receptor, ACE2, that exists in human lungs.
While similarities seen in fatal viruses may not be good news, it implies that treatments that worked for SARS patients may work for Wuhan coronavirus patients.
A vaccine is reportedly in development but has not yet been approved or released. In the meantime, the study authors suggest that antibodies produced by patients already infected with the coronavirus could be used “to neutralize the virus,” per Business Insider.
Don't bother explaining. It goes like this:
Donny defenders: HCQ cures COVID 100%. President said so.
Study 1: HCQ does not work.
Donny defenders: You just need to add azithromycin!
Study 2 and Study 3: Nope, does not work.
Donny defenders: Add Zinc! Zinc solves everything!
Study 4: Nope, still nothing.
Donny defenders: You're using wrong dozing. Too much HCQ does not work.
Study 5, 6, 7: 3 different lower dosages do no work either.
Donny defenders: You're using it on very sick people, of course it does not work. Need to use it preventively.
Study 8, 9: Still nope. People who take it for lupus/malaria still get sick with COVID-19. Does not work for healthy people either.
Donny defenders: BiG FARma HIdiNg TeH TRuTH!
Again, same thing is true for almost all other drug resistance strains of a given disease. But the way the drugs work (or dont work) changes. Just because it infects humans the same way doesn't mean it'll respond the same way to the same compounds. Even that article you just posted says they may not be able to be treated the same.It actually does because it infects humans the same.
But it does work and it's censored by big tech.Again, same thing is true for almost all other drug resistance strains of a given disease. But the way the drugs work (or dont work) changes. Just because it infects humans the same way doesn't mean it'll respond the same way to the same compounds. Even that article you just posted says they may not be able to be treated the same.
Also i feel the need to point out there's a difference between similarly and identity from a genetic standpoint. And that difference can be quite critical.
They are still taking down videos of doctors telling people it works that they've used it and that people are fine.
Because she's treated people with it and it has worked?Why would you take advice from a crazy Nigerian pediatrician/preacher who believes aliens DNA is used to create vaccines?
Why would you take advice from a crazy Nigerian pediatrician/preacher who believes aliens DNA is used to create vaccines?
MineI didn't say that, what post are you quoting?
How exactly does she know it was the drug that caused patients to get better? If only there were a process to determine that....Because she's treated people with it and it has worked?
Who cares about her beliefs?
Why ban a drug that has been on the list of essential drugs for over 100 years?
Because she's treated people with it and it has worked?
I was talking about the video of a press conference of people in white coats on the steps of supreme court paid by Tea Party patriots claiming the government is hiding the covid cure and that we do not need wear masks. One of the people in white coats was a crazy lady preacher. The video gets removed by most of the platforms.I didn't say that, what post are you quoting?
Whatever POTUS says, needs to be defended to the death. At least until he changes his mind.Don't bother explaining. It goes like this:
Donny defenders: HCQ cures COVID 100%. President said so.
Study 1: HCQ does not work.
Donny defenders: You just need to add azithromycin!
Study 2 and Study 3: Nope, does not work.
Donny defenders: Add Zinc! Zinc solves everything!
Study 4: Nope, still nothing.
Donny defenders: You're using wrong dozing. Too much HCQ does not work.
Study 5, 6, 7: 3 different lower dosages do no work either.
Donny defenders: You're using it on very sick people, of course it does not work. Need to use it preventively.
Study 8, 9: Still nope. People who take it for lupus/malaria still get sick with COVID-19. Does not work for healthy people either.
Donny defenders: BiG FARma HIdiNg TeH TRuTH!