Humankind is hugely impractical in space, very unhealthy and dangerous for the people we send up, and its massively slowing our progress, that's the point.The propose is expansion of Humankind, we already use probes to explore, lets move beyond that.....
With robots we can take far greater risks, get much higher return on investment, and move more quickly towards actually colonizing Mars and setting up moon mining operations and the like.
We know enough now that humans living in spacestations or space craft for years on end just isn't a good idea, and they will be meat-cargo to transport through automated systems to get from A to B.
What we have moved beyond is the need for astronauts thanks to advances in software programming and robotics.