The module slot is wide enough but about 1/4" too short, would have to place the board in there without the I/O plate or try to trim it. That isn't figuring in any stand offs used on the board. If you wanted to cut out the hwic spots you would be about 1/2" short on the width and run into height issues again. Interesting build idea though... It could be done but wouldn't be pretty unless you tried to do an acrylic back plate or something though.