Vertical mice & trackballs can help if you prefer such shapes & have pain with using regular mice. Though what is most critical is proper rest for the arms & hands, massages, stretches, nutrition and strength training (Do some curls with light weights for example). The key is preventative...
The gaming label is mainly marketing though programmable keys are really nice, for around that price a few months ago (I haven't checked recently) Mistel also sells a split keyboard called the "barocco"; for me personally for around that price range of slightly above 100USD, getting something...