I doubt you'll have a problem. Beyond the setting I think the game has more in common with MMOs than it does with the original Guild Wars. Some of the mechanics are a bit different, but really easy to figure out.Does anyone have a primer for this game from the perspective of someone who is familiar with MMOs but never played Guild Wars? I know their website has a lot of information but I'd like a better breakdown of classes, skills, special abilities, explanation of acronyms, maybe a wiki of some sort?
http://wiki.guildwars2.com/wiki/Main_Page