I run mostly TF2, L4D, Unreal tournament 3 on my core 2 duo 6600 with 4 gigs of ram, and I have a 460 watt power supply and my current card is a Nvidia GTS with 640 mb ram, which gives me pretty low frames in those games. I'm looking to also play bioshock 2 when it comes out and mass effect 2 as well, also get better frames in Fallout 3 with maxed details. Thanks.