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It depends on how you define "modern", but Zotac makes a Fermi-based part.I can't find a single 1x card with a modern chipset.
I doubt it. Any chance on using a 16x card instead?
1 x PCI Express x16 slot, running at x16 (PCIEX16)
* For optimum performance, if only one PCI Express graphics card is to be installed, be sure to install it in the PCIEX16 slot.
1 x PCI Express x16 slot, running at x8 (PCIEX8)
* The PCIEX8 slot shares bandwidth with the PCIEX16 slot. When the PCIEX8 slot is populated, the PCIEX16 slot will operate at up to x8 mode.
1 x PCI Express x16 slot, running at x4 (PCIEX4)
* The PCIEX4 slot is available only when an Intel 22nm (Ivy Bridge) CPU is installed.
* The PCIEX4 slot shares bandwidth with the PCIEX8 and PCIEX16 slots. When the PCIEX4 slot is populated, the PCIEX16 slot will operate at up to x8 mode and the PCIEX8 will operate at up to x4 mode.
(The PCIEX16, PCIEX8 and PCIEX4 slots conform to PCI Express 3.0 standard.)
* PCIE Gen.3 is dependent on CPU and expansion card compatibility.
If you're using PCIe 3.0, then the performance hit dropping to 4x speed will be NEAR ZERO, especially if you're only using a single GPU to game with.
Proof is in this article, where at the highest resolution PCIe 3.0 4x delivers 98% of 16x at the highest resolution!